NFL: Los Angeles Rams host New York Giants in Monday Night Football clash
On Monday, September 21, the Los Angeles Rams host the New York Giants at SoFi Stadium in a Week 2 NFL matchup, with the Rams installed as clear favorites despite a poor season-opening performance.
Game context
Week 2 of the 2026 NFL season features a Monday Night Football matchup between the New York Giants and the Los Angeles Rams. The game is being played at SoFi Stadium in Inglewood, California, kicking off at 8:15 p.m. ET, and is broadcast on ESPN and ABC.
According to Covers.com, the Rams entered the game as favorites, with a point spread of -7.5 (Giants +7.5), while the total was set at 48.5 points. The moneyline market gave the Rams roughly a 75% implied win probability, compared to about 26% for the Giants.
Team form
The Giants delivered an impressive prime-time performance last week against Dallas, with the two teams combining to convert 17 of 22 third-down attempts and score on all seven combined red-zone trips, producing a high-scoring contest. That performance has raised hopes the Giants' offense can carry momentum into this road game.
The Rams, by contrast, are described in the source as having played poorly in their season-opening game in Australia, and the team is without defensive standout Myles Garrett, with the Rams' defense ranking third-worst in the league by success rate. In Week 1, the Rams ran three-tight-end sets on 38% of snaps — the second-highest rate in the league — and leaned heavily on the run.
Veteran Rams quarterback Matthew Stafford is looking to avoid an 0-2 start to the season after a Week 1 loss. On the Giants' side, attention is on quarterback Jaxson Dart, who showed strong rushing upside in Week 1 and could see even more scrambling opportunities if the Giants find themselves trailing.
Predictions and trends
Covers.com's top pick for the game is the Under 48.5 total points, anticipating a slower-paced, clock-consuming contest. The preview also highlights potential first-touchdown or anytime-touchdown candidates: Rams tight end Colby Parkinson, Giants quarterback Jaxson Dart, and Giants tight end Isaiah Likely.
The source also notes a betting trend: the Rams have covered the spread in eight of their last nine games following a straight-up loss.
